Switching off cancer genes

 
PROGEN Pharmaceuticals is making progress in a technology aiming to ‘switch off’ cancerous genes. 
A pre-clinical study found that Progen’s epigenetic technology is able to inhibit tumour-suppressing enzymes. CEO Justus Homburg is excited about the results.
“In epigenetics we try to switch genes to change how that cell behaves, how to stop it being cancerous rather than saying cancer cells are bad and let’s kill them off — it represents a big shift in the paradigm and that’s why epigenetics is so exciting,” explains Homburg.
But drug development is a lengthy process and Homburg predicts it could be another six years before the product PG11144 is fully developed and on the market as the first, second and third phases of trials still need to be carried out.
“Could it be a long term development? Yes, that could very well be the case, but it’s something well worth pursuing because it is a dramatic change,” he says.
Homburg points out the very risky nature of the drug development industry but he believes the technology’s potential is backed up by the data that shows it does have an effect on tumours.
“We think there’s an opportunity out there, but the vast majority of drug developments don’t succeed,” he says.
“We may be only able to target a specific cancer or a specific disease of a specific cancer – there’s a lot to learn but it’s potentially quite groundbreaking.”
Homburg is confident that Progen is in a good financial position and is comfortable with the company’s patent on the technology.
“One of the things to bear in mind is that we’ve been through a lot of corporate turmoil, but we have been able to put an awful lot of that behind ourselves and during that time pursued research in all of our products,” he says.
“These latest findings prove we have the technology, the expertise and the resources to progress our strong product pipeline.”

Enjoyed this article?

Don't miss out on the knowledge and insights to be gained from our daily news and features.

Subscribe today to unlock unlimited access to in-depth business coverage, expert analysis, and exclusive content across all devices.

Support independent journalism and stay informed with stories that matter to you.

Subscribe now and get 50% off your first year!

WorldFirst offers fast and secure cross-border payments to boost global sales for SMEs
Partner Content
WorldFirst, a one-stop digital payment and financial services platform for global busin...
Advertisement

Related Stories

Quantum Brilliance selected for $57m German project to develop world’s first mobile quantum computer

Quantum Brilliance selected for $57m German project to develop world’s first mobile quantum computer

Canberra-based computing hardware group Quantum Brilliance, in part...

JOLT launches in Canada with plans to grow EV fast-charge network to 5,000 locations

JOLT launches in Canada with plans to grow EV fast-charge network to 5,000 locations

Australian electric vehicle fast-charger provider JOLT has launched...

Climate change threatens Australian tourism more than is widely believed. Here’s why

Climate change threatens Australian tourism more than is widely believed. Here’s why

Right now, Australia is one of the top five tourist destinations in...

Former director of collapsed Berndale Capital Securities pleads guilty to dishonesty

Former director of collapsed Berndale Capital Securities pleads guilty to dishonesty

A former director of the collapsed Berndale Capital Securities has ...